David – Emergency Medicine Evidence

2 min 0

Miscellaneous

CAPE COD: Steroids for Severe Community Acquired Pneumonia

David
February 19, 2026

The CAPE COD trial was a multicentre, randomised, double-blind, placebo-controlled study evaluating early intravenous hydrocortisone…

5 min 0

Neurology

Management of Acute Ischaemic Stroke – Current Australian Guidelines

David
February 19, 2026

Intravenous Thrombolysis Endovascular Therapy Acute Antithrombotic Therapy Acute Blood Pressure Lowering Therapy Surgery for Acute…

7 min 0

Neurosurgery

Hypertonic Saline vs Mannitol for Raised Intracranial Pressure: Evidence Review

David
February 5, 2026

Bottom line from the best-available synthesis: both agents lower ICP; HTS has the more consistent…

2 min 0

Miscellaneous

RENOVATE: HFNP vs NIV in Acute Respiratory Failure

David
March 4, 2025

RENOVATE Trial: High-Flow Nasal Oxygen vs. Noninvasive Ventilation in Acute Respiratory Failure RENOVATE Investigators and…

6 min 0

Airway

PREOXI: Noninvasive Ventilation for Preoxygenation during Emergency Intubation

David
June 14, 2024

Conclusion: Preoxygenation with noninvasive ventilation results in less critical hypoxia than with face mask oxygen…

8 min 0

Miscellaneous

Quick Hits

David
June 13, 2024

Here are quick summaries of interesting papers to inform your practice Jan 2025 Early Restrictive…

4 min 0

Airway

FAKT: Fentanyl vs placebo with Ketamine and Rocuronium for ED RSI

David
June 3, 2024

Conclusion: There was no difference in rates of systolic blood pressure deviation outside of SBP…

5 min 0

Neonatal VL: Video vs Direct Laryngoscopy for Urgent Intubation of Newborn Infants

David
May 30, 2024

Conclusion: Video laryngoscopy resulted in a greater number of successful intubations on the first attempt…

5 min 0

Neurosurgery

ANNEXA-I: Andexanet for Factor Xa Inhibitor-Associated Acute Intracranial Haemorrhage

David
May 30, 2024

Conclusion: Use of andexanet in patients with ICH while taking a factor Xa inhibitor resulted…

3 min 0

Trauma

CRYOSTAT-2: Early and Empirical High-Dose Cryoprecipitate for Haemorrhage After Traumatic Injury

David
December 21, 2023

Conclusion: The addition of early empirical cryoprecipitate does not improve all-cause mortality in bleeding trauma…